Paper Type |
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Research Paper |
Title |
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HPTLC Method Development and Validation for Standardization of Drynaria Quercifolia Rhizome Powder |
Country |
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India |
Authors |
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S.S. Rajendran, M.Sowmiya, Neelaveni Thangavel, Vytheeswari Kadhirvel, Abinaya.N |
Page No. |
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01-10 |
Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease affecting 0.5–1% of adults worldwide, with women exhibiting a 2–3 times higher prevalence than men. Current therapeutic options, including non-steroidal anti-inflammatory drugs, disease modifying anti-rheumatic drugs, glucocorticoids, immunosuppressants, and biological agents, often present limitations such as adverse effects and high cost. This has led to increased interest in plant-based alternatives. Drynaria quercifolia known as 'Mudavaatukkal' in Tamil and traditionally used in Indian ethnomedicine, has been reported to treat various ailments, including rheumatism.........
Keywords : Drynaria quercifolia, Standardization, HPTLC, β-sitosterol.
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Vaidya VV, Patil SH, Ghadge DD, Shah HR. Physicochemical standardization and metal analysis of Drynaria quercifolia (L.) J. Sm. World Journal of Pharmaceutical Research. 2016 Apr 22;5(6):2140-8.
Paper Type |
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Research Paper |
Title |
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Chemical Stability of Compounded Atorvastatin Suspension Over a 5-week Period at Varied Temperature and Storage Conditions |
Country |
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USA |
Authors |
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Jace Swingle, Madison Grilliot, Julie Oestreich, Richard Dudley |
Page No. |
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11-16 |
Background: Atorvastatin, an inhibitor of 3-hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase, is widely prescribed in adult and pediatric patients for its potent cholesterol lowering effect. However, atorvastatin is only commercially available in tablet form. Therefore, pharmacists have compounded atorvastatin suspension making the medication available to more pediatric patients and select adults unable to take tablets. Limited reports on the preparation of atorvastatin suspension and lack of chemical stability data has relegated pharmacists to prepare a maximum 2-week supply of suspension per United States Pharmacopeia (USP) guidelines..........
Keywords : Stability; Chemical stability; HPLC; Suspension; Physicochemical properties; US Pharmacopeia (USP).
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[5]. Oliveira MA, Yoshida MI, Belinelo VJ, Valotto RS. Degradation kinetics of atorvastatin under stress conditions and chemical analysis by HPLC. Molecules. 2013;18(2):1447-56.
Paper Type |
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Research Paper |
Title |
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Phytochemical and Potential Antidiabetic of Catharanthus roseus: A Review |
Country |
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Indonesia |
Authors |
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Resty Apriliani, Widya Kardela, Fitra Fauziah |
Page No. |
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17-24 |
Background: Diabetes as a global problem increases in prevalence worldwide. Treatment of diabetes mellitus currently uses synthetic drugs.As we know, synthetic drugs have many side effects. Therefore, some people use herbal medicine asan alternative to treat diseases. One of them is Catharanthus roseus. This plant is a herbal medicine that has the potential as antidiabetic. Material and Methods: This article reviews the phytochemical compounds and in vivo and in vitro antidiabetic activity testing of Catharanthus roseus in the last decade..........
Keywords : Antidiabetic;Catharanthus roseus; pharmacology;phytochemical.
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PERKENI. Pedoman Pengelolaan Dan Pencegahan Diabetes Melitus Tipe 2 Di Indonesia 2021. PB PERKENI; 2021.
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International Diabetes Federation. 10th ed.; 2021. www.diabetesatlas.org
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Putra RJS, Anisyah A, P HR. Kejadian Efek Samping Potensial Terapi Obat Anti Diabetes Pada Pasien Diabetes Melitus Berdasarkan Algoritme Naranjo. Pharm J Indones. 2017;2(2):45-50.
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Pandanwangi S, Zuniarto AA, Mubarok H. Analisa Drug Related Problems (Drps) Pasien Gagal Ginjal Dengan Komplikasi Diabetes Mellitus di RSUD X. Pharma Xplore J Ilmu Farm. 2018;3(1):170-183.
Paper Type |
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Research Paper |
Title |
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A Recent Review on Novel Derivatives of Hydroxychloroquine |
Country |
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India |
Authors |
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Aditi, Dr.Abhishek Soni, Ms.Pooja Devi |
Page No. |
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25-34 |
Malaria is an acute febrile disease that is caused due to the parasite infection, transmitted in humans by female anopheles mosquito bite. Malaria is one of the leading reasons of mortality worldwide, but the early detection and quick acting treatment can fend off these unpleasant results. In Africa and some Asian countries, malaria is the most common disease,while in other developed countries it occurs due to import from endemic countries. As early as the 2nd century BC Chinese people used sweet sagewort plant to cure malarial fever. Quinine began to be used as an anti-malarial drug much later..........
Keywords : Malaria, Hydroxychloroquine, Nano-technological strategies and Nanoject.
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Paper Type |
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Research Paper |
Title |
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Screening of Some Herbal Medicine Preparations for Anti-Diabetic Activity |
Country |
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Nigeria |
Authors |
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Ogundeko TO, Ogbole EA, Ebuga G, Hayab EM, Fwangan BA, Dangiwa DA, Gyang SS |
Page No. |
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35-41 |
Background: Management of Diabetes Mellitus (DM) has become a huge challenge in the present-day society owing to the increasing cost of medicine and the global economic meltdown. Seeking for cheaper, effective and natural alternatives is preferential as the world is now moving towards the use of medicinal plant therapy. There is need for authentication of already-existing herbal preparations for DM in order to ensure safety and efficacy. This study therefore aimed to experimentally evaluate the hypoglycemic activity of some acclaimed Anti-Diabetic Herbal Preparations (acADHP) used in parts of North-Central, Nigeria for herbal treatment of DM..........
Keywords : Herbal medicines; Diabetes mellitus; P. americana; V. amygdalina; Hypoglycemic activity; North-central, Nigeria.
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